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Types of antimicrobial agents

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What are Antimicrobial Agents? - Definition, Types with

There are mainly two classes of antimicrobial drugs: those obtained from natural sources (i.e. beta-lactam antibiotic (such as penicillins, cephalosporins) or protein synthesis inhibitors (such as aminoglycosides, macrolides, tetracyclines, chloramphenicol, polypeptides); and synthetic agents List of nine important antimicrobial agents:- 1. Phenol and Phenol Derivatives 2. Alcohols 3. Halogens 4

In contrast, the term antimicrobials include all agents that act against all types of microorganisms - bacteria (antibacterial), viruses (antiviral), fungi (antifungal) and protozoa (antiprotozoal) The phenols contain a large number of common antiseptics and disinfectants, among them phenol (carbolic acid) and creosote, while such bisphenols as hexyl resorcinol and hexachlorophene are widely used as antiseptic agents in soaps. Chlorine and iodine are both extremely effective agents and can be used in high dilution The most feasible explanation for the antimicrobial action of alcohol is denaturation of proteins. This mechanism is supported by the observation that absolute ethyl alcohol, a dehydrating agent, is less bactericidal than mixtures of alcohol and water because proteins are denatured more quickly in the presence of water 484, 485 Antibacterial agents are classified based on the type of action, source of antibacterial agent, and range of the spectrum. Rose belongs to the family Rosaceae. Hundred (n=100) species of roses are.

Classification of Anti‐Bacterial Agents and Their

  1. Overview of an Antimicrobial agents Introduction. Various types of infections and diseases could also be caused by various types of organism such as fungi, bacteria, virus etc., in humans and animals. The agents which inhibit or prevent the pathogenicity of microorganism is called antimicrobial agent
  2. There are three types of public health antimicrobials: sterilizers, disinfectants, and sanitizers. See Table 2. Sanitizers are the weakest public-health antimicrobials. They reduce bacteria on surfaces. 1 Some sanitizers may be used on food-contact surfaces such as countertops, cutting boards, or children's high chairs. The label will indicate how a sanitizer can be used
  3. INJURY TO THE PLASMA MEMBRANE - Brief • All cells are bound by a cell membrane. • And although the membranes of all cells are quite similar, those of bacteria and fungi differ from eukaryotic cells. • These slight differences allow for selective action of some antimicrobial agents
  4. Orla Condell, Carol Iversen, Shane Cooney, Karen A. Power, Ciara Walsh, Catherine Burgess, Séamus Fanning, Efficacy of Biocides Used in the Modern Food Industry To Control Salmonella enterica, and Links between Biocide Tolerance and Resistance to Clinically Relevant Antimicrobial Compounds, Applied and Environmental Microbiology, 10.1128/AEM.
  5. o acid retaining the enzymatic activity, drug-resistant bacteria can emerge easily

Biofilms are complex microbial architectures that attach to surfaces and encase microorganisms in a matrix composed of self-produced hydrated extracellular polymeric substances (EPSs). In biofilms, microorganisms become much more resistant to antimicrobial treatments, harsh environmental conditions, The present chapter will concentrate on the antimicrobial properties and uses of the various types of antimicrobial agents. Cross-references to other chapters are made where appropriate. A comprehensive summary of inhibitory concentrations, toxicity and uses is provided by Wallhausser (1984). 2 Phenol Silver has been used as an example of antimicrobial agents since Hippocrates first described silver's antimicrobial properties in 400 B.C. However, it wasn't until 1972 that scientists understood how silver works. Small amounts of silver disrupt bacteria's metabolism by preventing it from converting nutrients into energy, which inhibits.

C. How Antimicrobial Agents Work . Antimicrobials are classified by two different classification systems used simultaneously: 1. microbicidal or microbistatic - whether they kill or inhibit the growth - 2. by target site of the drug . Antimicrobial agents organized by site of action **5 Sites of Action or Targets of Antimicrobials . 1 ANTIMICROBIAL AGENT & MECHANISM OF RESISTANCE Julia Hartati, dr Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. If you continue browsing the site, you agree to the use of cookies on this website Antibiotics may have e.g., antibacterial, antifungal, antiviral, antiparasitic, or even anticancer activity. The term is loosely used as a synonym for more specific categories such as anticancer, antimicrobial, or antibacterial drug Antimicrobial Dressing Categories Antimicrobial dressings come in a variety of dressing formats, including alginate, collagen, foam, gauze, gelling fiber, hydrogel, and transparent dressings, as well as wound contact layers

Antibacterials are used to treat bacterial infections. Antibiotics are classified generally as beta-lactams, macrolides, quinolones, tetracyclines or aminoglycosides. Their classification within these categories depends on their antimicrobial spectra, pharmacodynamics, and chemical composition Some antimicrobial agents can have either effect (as noted above) based on dose level. An example is tetracycline: it is generally bacteriostatic but at high concentrations may be bactericidal. Since most antimicrobial agents have a specific effect on certain types of microorganisims, it is most helpful if specimens from the infected area can. The simple answer to this is - antimicrobial agents. A disinfectant is an antimicrobial agent. It is not necessary that a disinfectant will kill all the microorganisms. It is not as effective as sterilization. The process of sterilization kills all types of living forms but a disinfectant kills only certain types of microbes Plants and spice extracts have greatest antimicrobial activity. Antimicrobial activity potential of clove, oregano, cinnamon, and thyme essential oils and components, cinnamaldehyde, eugenol, carvacrol, and thymol have been reported in numerous literature. [ 12 ] Antimicrobial Pesticides. These types of pesticides [PDF] help slow the growth of human pathogenic microorganisms and are used in food processing plants, dairies, breweries, poultry houses and other animal feeding operations, hospitals, medical and dental clinics and offices,.

The quinolones, also known as the fluoroquinolones, are a synthetic, bactericidal antibacterial class with a broad-spectrum of activity. The quinolones can be used for difficult-to-treat urinary tract infections when other options are aren't effective, hospital-acquired pneumonia, bacterial prostatitis, and even anthrax or plague What is an antimicrobial agent? Antibiotics are a specific type of antimicrobial agent - they kill or limit the growth of microorganisms. Antimicrobial agents are not limited to antibiotics; chemicals like bleach or alcohol will kill bacteria, as will physical processes like heating or ionising radiation Ethyl alcohol, at concentrations of 60%-80%, is a potent virucidal agent inactivating all of the lipophilic viruses (e.g., herpes, vaccinia, and influenza virus) and many hydrophilic viruses (e.g., adenovirus, enterovirus, rhinovirus, and rotaviruses but not hepatitis A virus (HAV) 58 or poliovirus) 49 Examples include the β-lactam antibiotics that inhibit the bacterial cell wall synthesis, fluoroquinolones that inhibit DNA synthesis, tetracycline which is an inhibitor of protein synthesis,.. antimicrobial agents. agents that kill microorganisms or inhibit their growth. antibacterials. inhibit cell wall synthesis, alter membrane permeability, inhibit protein synthesis, inhibit nucleic acid synthesis, and/or interferes with cellular metabolism. types of antimicrobial drugs. antibacterial, antifungal, antiprotozoan, antihelminthic

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BioCote's unique range of Antimicrobial Additives can be easily and cost-effectively manufactured into all types of plastics and polymers including the following: Acrylonitrile butadiene styrene (ABS) Ethylene vinyl acetate (EVA) High impact polystyrene (HIPS Antimicrobial Resistance (AMR) occurs when bacteria, viruses, fungi and parasites change over time and no longer respond to medicines making infections harder to treat and increasing the risk of disease spread, severe illness and death Which of the following types of antimicrobial agents is capable of sterilization after long periods of exposure? aldehydes. Which of the following is NOT a factor affecting efficacy of an antimicrobial method? the biosafety level of the lab to be cleaned Antimicrobial therapy has proven to shorten duration of symptoms and reduce the risk of serious complications (77). Recommended antibiotics include azithromycin, cefixime, ceftriaxone, ciprofloxacin and levofloxacin. As with EPEC and ETEC, resistance to various antimicrobial agents has also been noted among EIEC. Enteraggregative E. coli (EAEC JCP Plastic is a Thailand-based manufacturer of kitchenware products.Their Super Lock antimicrobial food storage containers feature Microban protection, making them resistant to the negative effects of bacteria. Consumer who purchase Super Lock food containers can rest assured that their fruits and vegetables are nestled inside of a protected container that will not grow bacteria on its surface

Antimicrobial agent: A general term for drugs, chemicals, or other substances that either kill or slow the growth of microbes.Among the antimicrobial agents are antibacterial drugs, antiviral agents, antifungal agents, and antiparasitic drugs There may not be enough of the antibacterial or antimicrobial agent in these cleaning products to destroy bacteria completely. When exposed to antibacterial or antimicrobial cleaning products, most bacteria will die, but some may survive and multiply. These strains can become resistant to antibiotics and disinfectants Most microbiologists distinguish two groups of antimicrobial agents used in the treatment of infectious disease: antibiotics, which are natural substances produced by certain groups of microorganisms, and chemotherapeutic agents, which are chemically synthesized An antimicrobial additive is a substance that contains an appropriately registered antimicrobial agent. Integrated at the stage of manufacture, an antimicrobial additive will provide around-the-clock product protection from the growth of microbes including bacteria, fungi and algae Antimicrobial agent is a chemical substance derived from a biological source or produced by chemical synthesis that kills or inhibits the growth of microorganisms. The noun antibiotic was first used in 1942 by Dr. Selman A. Waksman, soil microbiologist. Dr. Waksman and his colleagues discovered several actinomycetes derived antibiotics

If the antimicrobial agent is microbiostatic, once it is removed the microorganism will usually recover and grow again normally. Factors that can influence the effectiveness of either type of antimicrobial action include the concentration of the agent as well as the type and nature of the target organisms Antimicrobial peptides (AMPs), also known as host defense peptides, are short and generally positively charged peptides found in a wide variety of life forms from microorganisms to humans. Most AMPs have the ability to kill microbial pathogens directly, whereas others act indirectly by modulating the host defense systems Today, a wide variety of chemicals called antimicrobial agents are available for controlling the growth of microbes. These include chemotherapeutic agents, disinfectants, and antiseptics Antibiotics and antimicrobial agents are increasingly being developed to fight against dental caries. In this review, Qiu et al. focused on discussing the application of systemic antibiotics and other antimicrobial agents with their clinical use to date, including the history of their development and their side effects, uses, structure types, and molecular mechanisms to promote a better. A special emphasis to silver nanoparticles is given, while others (e.g., gold, zinc oxide, copper, and copper oxide nanoparticles) commonly used in antibiotherapy are also reviewed

Therefore, overall risks to human health related to the particular antimicrobial agents need to be assessed separately in considering the specific application of each antimicrobial during the pre-market or post-market evaluation. The risk analysis or assessment is expected to include drug categorization and other relevant information The microwells contain serial dilutions of dehydrated antimicrobial agents. Three types of panel configurations for Gram-negative and three for Gram-positive bacteria are available: (i) Combo panels containing both antimicrobial dilutions and identification (ID) substrates; (ii) Breakpoint Combo panels containing antimicrobials in a breakpoint. It is noteworthy that therapeutic use of antimicrobial agents in animals has a close relationship with the drugs used in humans with respect to the types of drugs used . The increased therapeutic use in animals may contribute to a worse, drug-resistance scenario both in animals and humans Several types of antibacterial agents target bacterial protein synthesis by binding to either the 30S or 50S subunits of the intracellular ribosomes. This activity then results in the disruption of the normal cellular metabolism of the bacteria, and consequently leads to the death of the organism or the inhibition of its growth and multiplication

Types of Antimicrobial Agents - Russell, Hugo & Ayliffe's

Ans: An antimicrobial is a kind of an agent which tends to kill microorganisms or inhibits their growth. Antimicrobial medicines are divided based on their action against the microorganisms. An example is that antibiotics are used against the action of bacteria and antifungal medicines are used for treating fungal infections In contrast, antimicrobial agents kill susceptible organisms with profound and lasting consequences. Antimicrobials are often described as societal drugs because of the broad consequences of individual antimicrobial use on patient contacts, the local community, and potentially microbial populations worldwide The outermost layers of microbial cells can thus have a significant effect on their susceptibility (or insusceptibility) to antiseptics and disinfectants; it is disappointing how little is known about the passage of these antimicrobial agents into different types of microorganisms Major Targets of Common Antimicrobial Agents. Different classes of antimicrobial drugs have different mechanisms of action, owing to the nature of their chemical structure and specific affinities for target sites on or within bacterial cells. The image at left depicts some common antimicrobial agents attacking DNA, the cell wall, or ribosomes

Antimicrobial Agents Types Manufacturers, Factory, Suppliers From China, On account of superior excellent and aggressive rate , we will be the sector leader, make sure you don't hesitate to contact us by cellular phone or email, if you're fascinated in almost any of our items An antimicrobial is an agent that kills or inhibits the growth of microorganisms. The microbial agent may be a chemical compounds and physical agents. These agents interfere with the growth and reproduction of causative organisms like bacteria, fungi, parasites, virus etc • Antiseptic - Antimicrobial agent that is sufficiently non-toxic to be applied on living tissue • Sanitization - Lowering the number of microbes on eating and drinking utensils (by heat or chemical disinfectant) • Decontamination - Mechanical removal of microbes from organisms or non-living object

Antimicrobial agents, including various antibiotics and synthetic antibiotics that have bactericidal or bacteriostatic effects, are drugs that kill or inhibit the effects of bacteria [].In 1999, four classification methods were applied based on chemical structure, action mode, antimicrobial spectrum, and action mechanism of antimicrobial agents [] A type of antimicrobial agent used as a disinfectant, called a phenol, uses a similar process to kill off bacteria on inanimate objects through the inactivation of their enzyme systems. This is by.

A minireview and a short article, published in Antimicrobial Agents and Chemotherapy, a journal of the American Society for Microbiology, suggest that therapeutic drugs targeting SARS-CoV-2 directly will be most effective Antimicrobial is the general term for any product or ingredient that kills or inhibits bacteria, viruses, or molds. Antibacterials, on the other hand, are only effective against bacteria. Until recently, the main kinds of home antimicrobial products were disinfectants and antiseptics The term 'biocide' is increasingly being used to describe compounds with antiseptic, disinfectant or, sometimes, preservative activity. A compound might be used in only one such capacity or possess two or even all of these properties. 1 Until fairly recently, there were two long-held general opinions about biocides. The first was that, as long as they were effective, there was little. However, the term antibiotic is often used to refer to all types of antimicrobial agents. Figure 2 Zone diameter interpretive standards and approximate MIC correlates used to define the interpretive categories. Antimicrobial agent (amount per disk) and organism

ADVERTISEMENTS: Antimicrobial drugs are classified in a variety of ways. They are: 1. Classification Based on Cidal or Static Action 2. Classification Based on Mechanism of Action of the Drugs 3. Classification Based on Spectrum of Activity. 1. Classification Based on Cidal or Static Action: e.g. bactericidal or bacteriostatic (Table 25.1) and fungicidal or fungi [ Antimicrobial dressings deliver a sustained release of antimicrobial agents to the wound bed, which allows for a lower concentration of the agent and lowers the potential toxicity to host cells. These dressings typically get their antimicrobial activity from silver, iodine or polyhexamethylene biguanide (PHMB), and come in a variety of delivery. Although synthetic antimicrobial agents have been already approved in many countries, yet the usage of natural compounds that are derived from microbial, animals, or plants attracts the attention of many researchers [40, 41] 1. Antimicrobial Effects on Cells. Antimicrobials can be divided into two classifications based upon their effects on target cells. Drugs that actually kill microorganisms are termed bactericidal.Drugs that only inhibit the growth of microorganisms are termed bacteriostatic.The decision to use a bactericidal or bacteriostatic drug to treat infection depends entirely upon the type of infection One of the most durable types of antimicrobial products is based on diphenyl ether (bis-phenyl) derivative known as either 2, 4, 4'-trichloro-2' hydroxy dipenyl ether or 5-chloro-2-(2, 4-dichloro phenoxyl) phenol. Triclosan products have been used for more than 25 years in hospitals and personal care products such as antimicrobial soap.

MacConkey Agar- Composition, Principle, Uses, Preparation

About Press Copyright Contact us Creators Advertise Developers Terms Privacy Policy & Safety How YouTube works Test new features Press Copyright Contact us Creators. Antimicrobial agents - optimising the ecological balance Sze-Ann Woon1 and Dale Fisher1,2,3* Abstract Background: There is no more challenging a group of pharmaceuticals than antimicrobials. With the antibiotic era came great optimism as countless deaths were prevented from what were previously fatal conditions. Althoug These are antimicrobial agents against bacteria that can inhibit growth and help the body clear infections. Slide 3: Modes of action. There are several classes of antimicrobial agents against bacteria. Some agents, like the cell wall-targeting beta-lactams, are bactericidal; meaning, these agents kill the organism outright

Types of antimicrobial agents - Cam Borne Town Ban

Antimicrobial Agent - an overview ScienceDirect Topic

Emulsions (including semisolid or ointment-type emulsions):All emulsions require an antimicrobial agent because the aqueous phase is favorable to the growth of microorganisms. 2. Suspensions: Suspensions intended for any route of administration should contain suitable antimicrobial agents to protect against bacteria, yeast, and mold. We develop antimicrobial testing methods and standard operating procedures to measure the effectiveness of hard surface disinfectants against: Staphylococcus aureus. Pseudomonas aeruginosa. Salmonella choleraesuis. Mycobacterium bovis (BCG). Clostridium difficile. Viruses. Biofilm. Methods are available for the following types of antimicrobial. The following lists of antimicrobial products registered by EPA are effective against common pathogens, as indicated in the list titles. EPA-registered antimicrobial products may not make efficacy claims against these pathogens unless the Agency has reviewed data to support the claim and approved the claim on the label

Commonly Used Antimicrobial Drugs Boundless Microbiolog

Gene therapy

9 Important Antimicrobial Chemical Agent

The antimicrobial additives market is classified on the basis of type, namely, inorganic (silver, copper, and zinc) and organic (OBPA, DCOIT, and Triclosan). Silver is the major type of antimicrobial additive and accounted for the maximum share of the market in 2015 or other antimicrobial agents) due to study design and low SSI rates for most procedures. A small sample size increases the likelihood of a Type II error; therefore, there may be no apparent difference between the antimicrobial agent and pla-cebo when in fact the antimicrobial has a beneficial effect.1 Antimicrobial medicines can be grouped according to the microorganisms they act primarily against. Examples antibiotics, antifungals, antiprotozoal, and antiviral drugs. Antimicrobial medicines can be grouped according to the microorganisms they act primarily against

Antimicrobials: An Introduction — Antimicrobial Resistance

The surface-active agents provide better wetting and organic soil penetration, thus making iodophors less affected by soil than hypochlorite. The choice of surface-active agent may lead to foam generation in applications such as CIP. Iodophors have a broad antimicrobial spectrum 0017 that is similar to hypochlorite, although they are les Detergents are used primarily for leaning purposes but it has also antimicrobial properties. There are three types of detergents- Cationic detergent, anionic detergent and non-ionic detergent. Cationic detergents is more significant germicidal agent than other two

Pharmaceuticals | Free Full-Text | Antimicrobial Peptides

These proteins are needed for bacterial cell wall synthesis and are the targets of β-lactam antibiotics. The new penicillin-binding protein has low affinity to β-lactam antibiotics and is thus resistant to the drugs, and the bacteria survive treatment. This type of resistance is the basis in MRSA (methicillin-resistant Staphylococcus aureus) In this lesson, we'll be exploring the important topic of antimicrobial resistance. We'll cover what is causing this global problem and explore types and examples of antimicrobial resistance Antimicrobial agents Antimicrobial agents Type of paper Assignment Subject Nursing Number of pages 1 Format of citation APA Number of cited resources 4 Type of service Writing Antimicrobial Agents Antimicrobial agents are essential components in the treatment of various bacterial infections as they help to kill or prevent the growth of microbes such as bacteria, [

Dec 18, 2015 - types of antimicrobial agents chart - Google Search. Dec 18, 2015 - types of antimicrobial agents chart - Google Search. Pinterest. Upptäck. Logga in. Gå med. . Sparad från google.ca. Amning. types of antimicrobial agents chart - Google Search. Sparad av Taylor Arlis. 151. However, the majority of the other antimicrobial substances (clarithromycin, clindamycin, gentamicin, linezolid, tigecycline, vancomycin, and fluconazole) were neutralized so effectively that no, or nearly no, growth delay resulted Resistance to biocidal agents has been widely studied in bacteria 11 and to some extent in fungi, 27 with some useful information beginning to emerge with some types of protozoa (Table 5). 53 - 57 In non-sporulating bacteria, the major mechanisms of resistance are reduced uptake (impermeability and/or efflux), 11 with possible mutation. antifungal agents, etc.). In addition, the journal signals new trends and developments in the field through highly authoritative review articles on antimicrobial agents. Special attention is given to articles providing insight into the problems of antimicrobial resistance both in the hospital and in the community In this report, we disclose our effort to develop novel antimicrobial agents with a hybrid strategy 6,6b for myxopyronin derivatives. To enhance the antimicrobial activity, reduce the lipophilicity, and improve the instability, the antibiotic holomycin (4) 7 was incorporated into the mother skeleton of the myxopyronin-type RNAP inhibitors

Home remedies for paronychia - Home remedies

Antimicrobial agent pharmacology Britannic

therapy, (2) recognize different types of adverse effects of antimicrobial agents and modify antimicrobial therapy as appro-priate, and (3) identify clinical scenarios in which use of antimicrobial agents is inappropriate. Antimicrobial agents are some of the most widely, and often inju-diciously, used therapeutic drugs worldwide. Important. Types of metal-based antimicrobial nanoparticles Metallic and metal-oxide nanoparticles. Since ancient times, metal-based materials, such as silver and copper, have been used as antimicrobial agents by the Egyptians, Persians, Greeks and Romans The type of bacteria against which a particular antimicrobial agent does and does not have activity is referred to as that drug's spectrum of activity. Many factors contribute to an antibiotic's spectrum of activity, and knowledge of this spectrum is the key to many aspects of antimicrobial use and laboratory testing An antibiotic is a type of antimicrobial substance active against bacteria.It is the most important type of antibacterial agent for fighting bacterial infections, and antibiotic medications are widely used in the treatment and prevention of such infections. They may either kill or inhibit the growth of bacteria. A limited number of antibiotics also possess antiprotozoal activity 390 Antimicrobial Agents them.( Shahidi et al, 2010) Although some othe r metals, such as copper, zinc and cobalt, have attracted attention as effective antimicrobial agents for textiles, silver is by far the most widely used in general textiles as well as in wound dressings. It has a MIC value of 0.05 0.1 mg/l against E. coli

Chemical Disinfectants Disinfection & Sterilization

Inorganic Antimicrobial Agent Organic Antimicrobial Agent; Antimicrobial Effect: Slow-acting. Effective across a wide scope,including germs,mold and yeast. Fast-acting. The majority has limitations regarding which types they are effective on. Heat Resistance : Won't decompose or transform even at resin molding temperature (maximum 350˚C) Carbapenems are a unique class of β-lactam agents with the widest spectrum of antimicrobial activity of the currently available antimicrobial agents. Structurally, they differ from other β-lactams in the unique stereochemistry of the hydroxyethyl side chain that confers stability against β-lactamases

Necrotizing Soft Tissue Infections - Infectious Disease

Antimicrobial Flooring, Carpet and Rugs Antimicrobial Flooring, Carpet, and Rugs. Flooring, carpets, and rugs can frequently be a source of unwanted bacteria and fungi. Fungi can flourish in moist areas under soft flooring materials and create musty odors and loss of product integrity Antimicrobial susceptibility tests (ASTs) basically measures the ability of an antibiotic or other antimicrobial agent to inhibit the invitro microbial growth. There are many different procedures that microbiologists use to study the effects of various antimicrobial agents in treating an infection caused by different microorganisms the properties of the antiseptic agents, including effects on the skin and to contribute to the final decision regarding the antiseptic agents that are the most effective antimicrobial solutions as well as least harmful to the skin. The cost of the antiseptic agents should not be a factor that influences the decision-making process. B 1.3 This method can confirm the presence of antimicrobial activity in plastics or hydrophobic surfaces and allows determination of quantitative differences in antimicrobial activity between untreated plastics or polymers and those with bound or incorporated low water-soluble antimicrobial agents. Comparisons between the numbers of survivors on preservative-treated and control hydrophobic. Disinfectants are chemical agents designed to inactivate or destroy microorganisms on inert surfaces. Disinfection does not necessarily kill all microorganisms, especially resistant bacterial spores; it is less effective than sterilization, which is an extreme physical or chemical process that kills all types of life. Disinfectants are generally distinguished from other antimicrobial agents. A series of 1,2,3-triazole-derived naphthalimides as a novel type of potential antimicrobial agents were synthesized and characterized by IR, NMR and HRMS spectra. All the new compounds were screened for their antimicrobial activity against four Gram-positive bacteria, four Gram-negative bacteria and three fungi

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